Amsterdam is an ideal destination for solo travel, especially for female travelers! So much so that I recommend Amsterdam highly for any first-time solo female travelers. Here’s why: the city’s unique culture and liberal atmosphere make it welcoming and safe for visitors of all backgrounds. Additionally, Amsterdam has a well-connected public transport system and an abundance of attractions, making solo travel to Amsterdam overall convenient and stress-free.
I would not at all say the Red Light District is unsafe for solo female travelers. We would recommend to visit Red District during the day, but at night it looks more interesting. However, at night the Red Light District usually attracts some of Amsterdam’s worst tourists: namely very drunk, very rude, very lewd men.